Let’s Chat: Proteins, Platforms, Programs

Most bios tell you what someone has done. This is a chance to ask. I’m Marc, a structural biologist and drug discovery leader with two decades of experience across X-ray crystallography, Cryo-EM, protein engineering, and translational science. Rather than reading a static resume, you can ask me directly about my approach to structure-guided discovery, how I’ve built and led scientific platforms, what I look for when designing a drug discovery program, or where I think the field is heading. Think of this less as a chatbot and more as a conversation with me.

  • Fun questions to cut and paste:
  • If you could create a dream team of famous scientists (living or historical) to collaborate on tackling big problems, who would you choose and why?
  • Imagine you have unlimited resources to build the ultimate automated research platform for structural biology—what cool features and capabilities would it include?
  • What’s the wildest or most futuristic application of protein–ligand crystal structures you can envision for drug discovery or diagnostics?
  • If a plastic-eating enzyme like PETase could “talk,” what would it say about its role in cleaning up our planet—and what mutation would it request for its next upgrade?